The most important goals of I Tatti are to advance our understanding of the Italian Renaissance and to encourage the fruitful interchange of ideas. To this end, the center offers fifteen full-year post-doctoral I Tatti Fellowships annually, as well as several fellowships for shorter periods. The center provides a tranquil setting where scholars can exchange ideas and carry out their research. Fellows join a community of scholars from all over the world, working in a wide range of fields and often with different methodological approaches. I Tatti's academic community is rounded out with Research Associates, Visiting Professors, and the scholars on staff.

Former Fellows can apply for Lila Acheson Wallace – Reader’s Digest Special Grants to support their scholarship.